VitaminStrand fortificationN° 002

Biotin

Vitamin B7 · D-biotin

The keratin cofactor every fragile strand quietly runs out of.

Region
🇧🇪 Belgium · pharmaceutical-grade fermentation
Form
Water-soluble crystalline powder
Shelf life
36 months in sealed formulas
Category
Vitamin
The briefHow it worksMolecularSignalHeritageField → phialPairsFormulasFAQSources

01The brief.

Origin

Bio-fermented in a Belgian pharmaceutical facility using non-GMO yeast. Certified USP-grade and Kosher.

Extraction

Yeast fermentation produces the D-biotin isomer — the only stereoisomer the body can actually use. The crystallised active is then purified to >98% for cosmetic and pharmaceutical use.

Concentration

Topical: 0.05%–0.2%. Oral supplementation: 30–100 mcg / day is adequate for most adults; mega-doses can skew thyroid and troponin blood tests.

02How it works.

Biotin is a coenzyme in the carboxylase reactions that build keratin. When it's deficient, the body deprioritises hair and nail growth to protect vital organs. Topically delivered biotin bypasses gut absorption, targeting the follicle directly with the cofactor it needs to spin longer, stronger strands.

  • Benefits
  • ✦Cofactor for keratin synthesis — the protein 95% of your hair is built from
  • ✦Strengthens the cuticle, reducing breakage during brushing and styling
  • ✦Improves shine by tightening the outer scale layer of each strand
  • ✦Supports nail thickness and skin barrier as a bonus

03Molecular signature.

The active constituents that make Biotin work — with standardised percentages where measured by HPLC.

  • Bicyclic ureido ring

    The carbon backbone that binds carboxylase enzymes during keratin synthesis.

  • Tetrahydrothiophene ring

    Sulfur-containing ring that stabilises the molecule and helps it slip through the sebum layer.

  • Valeric acid tail

    The 'anchor' that lets biotin dock into the follicle keratinocyte.

04Signal profile.

EvidencePotencySafetyHeritageSensorySourcing

A living profile — the record that made Biotin the house's choice.

  • Evidence

    2 peer-reviewed sources

    74

  • Potency

    Standardised at 500 Da

    100

  • Safety

    Broad tolerance

    92

  • Heritage

    Documented across 4 traditions

    88

  • Sensory

    Vitamin profile

    58

  • Sourcing

    Traceable provenance

    78

05Heritage.

The record

Discovered in 1927 by Margarete Boas as 'protective factor X' in egg yolks, biotin was isolated in 1936, structurally decoded by Nobel laureate Vincent du Vigneaud in 1942, and added to the essential-vitamin registry the same decade. It has been trichology's default hair vitamin ever since.

Traditional use

Long before its isolation, egg-yolk hair masks — biotin's richest natural source — were a staple of North African and Indian hair care.

Naturally found in

  • ●Egg yolks (richest natural source)
  • ●Liver, salmon, sunflower seeds
  • ●Sweet potato and almonds
  • ●Nutritional yeast

Sustainability

Fermentation-derived, so no animal inputs and no land-use footprint. The Belgian facility runs on 100% renewable electricity.

06Field → phial.

Every gram of Biotin passes five gates before it enters a Ghori formula. No shortcuts, no re-labels — the paper trail runs from soil to seal.

  1. 𖤣01

    Stage 01

    Harvest

    Bio-fermented in a Belgian pharmaceutical facility using non-GMO yeast. Certified USP-grade and Kosher.

  2. ❋02

    Stage 02

    Extract

    Yeast fermentation produces the D-biotin isomer — the only stereoisomer the body can actually use. The crystallised active is then purified to >98% for cosmetic and pharmaceutical use.

  3. ◇03

    Stage 03

    Assay

    HPLC-verified. 500 Da standardised for molecular weight — small enough to penetrate the follicle.

  4. ◉04

    Stage 04

    Formulate

    Topical: 0.05%–0.2%. Oral supplementation: 30–100 mcg / day is adequate for most adults; mega-doses can skew thyroid and troponin blood tests.

  5. ⌘05

    Stage 05

    Deliver

    Stable 36 months in sealed formulas. Sealed under nitrogen where required.

07Best for. Pairs with.

Best for

  • Brittle strands that snap mid-length
  • Post-diet, post-partum, or high-stress shed
  • Anyone with soft, peeling nails alongside hair thinning

Works well with

  • Rosemary Leaf Oil
  • Peppermint Oil
  • Hydrolyzed Keratin

08In 2 formulas.

09People often ask.

Does topical biotin actually reach the follicle?

Yes — biotin is a small, water-soluble molecule that passes through the sebaceous canal to the dermal papilla when carried in an oil or serum base.

Can I take biotin supplements too?

You can, but topical delivery is more targeted. If supplementing, stay under 100 mcg / day — mega-doses can skew lab test results.

Will biotin thicken my existing hair?

Individual strands can become measurably thicker within 8–12 weeks as new keratin is built with adequate cofactor supply.

10The paper trail.

  1. 01Patel DP, et al. Skin Appendage Disord. 2017 — A review of the use of biotin for hair loss.
  2. 02Trüeb RM. Int J Trichology. 2016 — Serum biotin levels in women complaining of hair loss.

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